國際婦產科超音波(International Society of Ultrasound in Obstetrics and Gynecology,ISUOG)診斷guideline也提到第一孕期(11週又0天至13週又6天)可用超音波看胎頭構造、腦部早期發育包括腦室及脈絡叢的形成。英國maternal-fetal medicine亦提到第一孕期早期診斷AEAS可到六成左右。
名詞釋義
Acrania:無頭蓋骨(abscence of fetal calvarium)讓腦組織曝露在羊水之中。
Acrania-exencephaly-anencephaly sequence phenotypic characterization using two- and three-dimensional ultrasound between 11 and 13 weeks and 6 days of gestationJ Ultrason. 2018; 18(74): 240–246.
P13.21: “Beret” sign in differentiating between anencephaly and exencephaly during ultrasound at the first and the second trimester (First published: 07 September 2012,ISOUG)