reference: The Economist
Eske Willerslve, an expert in ancient DNA, was recently asked to convince a jury that he could contribute to another field entirely: crime scene investigation.
The crime was the murder of a girl named Emilie Meng, a 17-year-old Danish girl whose strangled body was found in a lake. The police had hoped to find valuable DNA evidence from her trousers, but the trousers had been exposed for six months, resulting in less useful material due to significant damage. Desperate for answers, the police turned to Dr Willerslev.
The forensics community is rightly conservative when it comes to using new technology that could help. That's why they start taking up some new inventions.
DNA is composed of four distinct molecules called bases, which are arranged in combinations to form long polymer chains. These chains are linked together in pairs through bonds between their bases, resulting in the well-known double-helix structure of DNA. At specific locations along the chains, short sequences of bases are repeated multiple times, forming what are known as short tandem repeats (STRs).The number of short tandem repeats (STRs) at each genetic locus varies among individuals, enabling DNA samples to be matched to their owner by measuring the number of repeats.
Locations where individual pairs of nucleotides differ between people are called single nucleotide polymorphisms (SNPs). Scientists often identify tens of thousands of such sites. Dr Willersleve had obtained SNPs from Meng's trousers. Then he tried to identify whom they could have come from.