《我是運科竹：每週閱讀一段運動科學相關文獻，強化英文閱讀理解力以及運動科學相關知識》
Sarcopenia is a systemic skeletal muscle disease characterized by a decline in skeletal muscle mass and function. Originally defined as an age-associated condition, sarcopenia presently also encompasses muscular atrophy due to various pathological factors, such as intensive care unit-acquired weakness, inactivity, and malnutrition. The exact pathogenesis of sarcopenia is still unknown; herein, we review the pathological roles of the neuromuscular junction and mitochondria in this condition. Sarcopenia is caused by complex and interdependent pathophysiological mechanisms, including aging, neuromuscular junction impairment, mitochondrial dysfunction, insulin resistance, lipotoxicity, endocrine factors, oxidative stress, and inflammation.
文獻來源
Miao, Y., Xie, L., Song, J., Cai, X., Yang, J., Ma, X., Chen, S., & Xie, P. (2024). Unraveling the causes of sarcopenia: Roles of neuromuscular junction impairment and mitochondrial dysfunction. Physiological Reports, 12(1), e15917. https://doi.org/10.14814/phy2.15917
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陳映竹！ (Chen, Ying-Chu)，Ph.D. Student, M.S., M.A., CSCS*D, ACSM-EP-C.
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陳映竹同時擁有臺師大國際漢學研究所文學碩士，以及臺北市立大學運動健康科學系理學碩士。目前為臺師大體育與運動科學博士班學生。希冀透過平台持續推廣運動與健康科學相關知識，以及肌力與體能相關訓練理論及實務，並提供個人跨領域與教練自我成長歷程，讓有志從事教練產業以及斜槓工作者有所依循。